{"id":3490,"date":"2026-05-02T11:15:16","date_gmt":"2026-05-02T10:15:16","guid":{"rendered":"https:\/\/livingdiabetes.com\/egfr-calculator\/"},"modified":"2026-05-02T11:26:26","modified_gmt":"2026-05-02T10:26:26","slug":"egfr-calculator","status":"publish","type":"page","link":"https:\/\/livingdiabetes.com\/ur\/egfr-calculator\/","title":{"rendered":"eGFR Calculator (CKD-EPI 2021, Race-Free) \u2014 Kidney Function in Diabetes"},"content":{"rendered":"<p><strong>Estimate your kidney filtration rate (eGFR) from a recent creatinine blood test.<\/strong> Diabetes is the leading cause of chronic kidney disease \u2014 annual eGFR is part of the standard NICE NG28 review. This calculator uses the 2021 CKD-EPI equation (race-free), the version recommended by NICE, NHS England, and the National Kidney Foundation.<\/p>\n\n\n\n<style>\n.ld-calc{max-width:720px;margin:1.5em 0;padding:1.5em;border:1px solid #d4dde5;border-radius:8px;background:#f8fafc;font-family:inherit}\n.ld-calc h3{margin-top:0;color:#1a4870;font-size:1.25em}\n.ld-row{display:flex;flex-wrap:wrap;gap:.75em;margin-bottom:.85em;align-items:center}\n.ld-row label{flex:1 1 230px;font-weight:600}\n.ld-row input,.ld-row select{flex:0 0 150px;padding:.5em .65em;font-size:1em;border:1px solid #b8c5d3;border-radius:4px;background:#fff}\n.ld-row input:focus,.ld-row select:focus{outline:none;border-color:#1a8cb6;box-shadow:0 0 0 3px rgba(26,140,182,.15)}\n.ld-result{margin-top:1.25em;padding:1em 1.25em;background:#e8f4f9;border-left:4px solid #1a8cb6;border-radius:4px;font-size:1.02em}\n.ld-result .big{font-size:1.4em;font-weight:700;color:#0d5a78;margin-bottom:.25em}\n.ld-result .pill{display:inline-block;padding:.25em .7em;border-radius:999px;font-size:.85em;font-weight:600;margin-left:.5em;color:#fff}\n.ld-btn{display:inline-block;background:#1a8cb6;color:#fff;border:none;padding:.65em 1.4em;border-radius:4px;font-size:1em;cursor:pointer;font-weight:600;margin-top:.5em}\n.ld-btn:hover{background:#147099}\n.ld-disc{margin-top:1em;padding:.75em 1em;background:#fef9e7;border-left:3px solid #d4a017;border-radius:3px;font-size:.9em}\n@media (max-width:520px){.ld-row label{flex-basis:100%}.ld-row input,.ld-row select{flex-basis:100%}}\n<\/style>\n\n<div class=\"ld-calc\">\n<h3>eGFR Calculator (CKD-EPI 2021, race-free)<\/h3>\n<div class=\"ld-row\"><label for=\"lde-creat\">Serum creatinine<\/label><input type=\"number\" id=\"lde-creat\" step=\"0.01\" min=\"0.1\" max=\"20\" placeholder=\"e.g. 0.9 or 80\"><\/div>\n<div class=\"ld-row\"><label for=\"lde-units\">Creatinine units<\/label>\n<select id=\"lde-units\"><option value=\"mgdl\">mg\/dL (US)<\/option><option value=\"umol\">\u00b5mol\/L (UK \/ EU)<\/option><\/select>\n<\/div>\n<div class=\"ld-row\"><label for=\"lde-age\">Age<\/label><input type=\"number\" id=\"lde-age\" step=\"1\" min=\"18\" max=\"100\" placeholder=\"years\"><\/div>\n<div class=\"ld-row\"><label for=\"lde-sex\">Sex at birth<\/label>\n<select id=\"lde-sex\"><option value=\"female\">Female<\/option><option value=\"male\">Male<\/option><\/select>\n<\/div>\n<button type=\"button\" class=\"ld-btn\" id=\"lde-calc\">Calculate eGFR<\/button>\n<div class=\"ld-result\" id=\"lde-out\" style=\"display:none\"><\/div>\n<div class=\"ld-disc\">eGFR is an <em>estimate<\/em>. People with very high or very low muscle mass, amputations, or unusual diets may need cystatin-C-based estimation (CKD-EPI Cr-Cys) for accuracy. This is a screening tool \u2014 your renal team interprets your full picture.<\/div>\n<\/div>\n\n<script>\n(function(){\ndocument.getElementById('lde-calc').addEventListener('click',function(){\nvar creat=parseFloat(document.getElementById('lde-creat').value);\nvar units=document.getElementById('lde-units').value;\nvar age=parseFloat(document.getElementById('lde-age').value);\nvar sex=document.getElementById('lde-sex').value;\nif(!creat||!age){alert('Please fill in creatinine and age');return;}\n\/\/ Convert \u00b5mol\/L \u2192 mg\/dL if needed\nif(units==='umol') creat = creat \/ 88.4;\n\/\/ CKD-EPI 2021 race-free\n\/\/ eGFR = 142 \u00d7 min(Scr\/\u03ba,1)^\u03b1 \u00d7 max(Scr\/\u03ba,1)^-1.200 \u00d7 0.9938^age \u00d7 (1.012 if female)\nvar kappa = sex==='female' ? 0.7 : 0.9;\nvar alpha = sex==='female' ? -0.241 : -0.302;\nvar ratio = creat\/kappa;\nvar a = Math.pow(Math.min(ratio,1), alpha);\nvar b = Math.pow(Math.max(ratio,1), -1.200);\nvar egfr = 142 * a * b * Math.pow(0.9938, age);\nif(sex==='female') egfr *= 1.012;\negfr = Math.round(egfr);\nvar stage,advice,color;\nif(egfr>=90){stage='G1 \u2014 Normal or high';advice='Normal kidney function. (G1 only counts as CKD if there are other markers like protein in the urine.)';color='#2a7a3a';}\nelse if(egfr>=60){stage='G2 \u2014 Mildly decreased';advice='Mild reduction. Counts as CKD only if combined with protein in urine or other damage markers. Annual eGFR + uACR is standard.';color='#5e8c2a';}\nelse if(egfr>=45){stage='G3a \u2014 Mildly to moderately decreased';advice='Stage 3a CKD. Discuss kidney-protective medication (ACE\/ARB if albuminuria, SGLT2 inhibitor) with your team. Avoid nephrotoxic drugs (NSAIDs).';color='#c97f2a';}\nelse if(egfr>=30){stage='G3b \u2014 Moderately to severely decreased';advice='Stage 3b CKD. Closer monitoring needed. SGLT2 inhibitors and finerenone are now key treatments. Many medications need dose adjustment.';color='#d96f1c';}\nelse if(egfr>=15){stage='G4 \u2014 Severely decreased';advice='Stage 4 CKD. Refer to a nephrologist if not already seen. Plans for dialysis or transplant should start being made.';color='#c44';}\nelse {stage='G5 \u2014 Kidney failure';advice='Kidney failure. Dialysis or transplant required (or active conservative management).';color='#a22';}\nvar html='<div class=\"big\" style=\"color:'+color+'\">eGFR '+egfr+' ml\/min\/1.73m\u00b2<\/div>'+\n'<div style=\"margin-top:.5em\"><strong>Stage:<\/strong> <span class=\"pill\" style=\"background:'+color+'\">'+stage+'<\/span><\/div>'+\n'<div style=\"margin-top:.6em\">'+advice+'<\/div>'+\n'<div style=\"margin-top:.6em;font-size:.92em\">A single eGFR doesn\\'t diagnose CKD \u2014 diagnosis requires either eGFR &lt;60 OR a urine ACR \u22653 mg\/mmol, sustained over 3 months.<\/div>';\ndocument.getElementById('lde-out').innerHTML=html;\ndocument.getElementById('lde-out').style.display='block';\n});\n})();\n<\/script>\n\n\n\n<h2 class=\"wp-block-heading\">What eGFR measures<\/h2>\n\n\n\n<p>eGFR (estimated glomerular filtration rate) is the best single number for kidney function \u2014 how much blood the kidneys can filter per minute. The number is &#8220;estimated&#8221; because it&#8217;s calculated from a blood test (creatinine), age, and sex rather than measured directly. The 2021 CKD-EPI equation is the version that NICE, NHS England, and the National Kidney Foundation now recommend; the older &#8220;MDRD&#8221; equation has been retired.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">CKD stages by eGFR<\/h2>\n\n\n\n<figure class=\"wp-block-table\"><table><thead><tr><th>Stage<\/th><th>eGFR (ml\/min\/1.73m\u00b2)<\/th><th>\u062a\u0641\u0635\u06cc\u0644<\/th><\/tr><\/thead><tbody>\n<tr><td>G1<\/td><td>\u2265 90<\/td><td>Normal or high<\/td><\/tr>\n<tr><td>G2<\/td><td>60 \u2013 89<\/td><td>Mildly decreased<\/td><\/tr>\n<tr><td>G3a<\/td><td>45 \u2013 59<\/td><td>Mildly to moderately decreased<\/td><\/tr>\n<tr><td>G3b<\/td><td>30 \u2013 44<\/td><td>Moderately to severely decreased<\/td><\/tr>\n<tr><td>G4<\/td><td>15 \u2013 29<\/td><td>Severely decreased<\/td><\/tr>\n<tr><td>G5<\/td><td>&lt; 15<\/td><td>Kidney failure<\/td><\/tr>\n<\/tbody><\/table><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Why diabetes makes kidney monitoring critical<\/h2>\n\n\n\n<p>Diabetes is the single biggest cause of chronic kidney disease worldwide. Damage progresses silently for years before symptoms appear. NICE NG28 recommends both eGFR <strong>and<\/strong> a urine albumin-to-creatinine ratio (uACR) at least once a year for everyone with diabetes \u2014 uACR picks up albumin leak in the urine before eGFR falls.<\/p>\n\n\n\n<p>The combination matters: a person with eGFR 75 and uACR 5 has CKD even though their eGFR alone looks fine. A person with eGFR 75 and uACR &lt;3 doesn&#8217;t.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What slows progression<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Tight blood pressure control<\/strong> with an ACE inhibitor or ARB if there&#8217;s albuminuria.<\/li>\n<li><strong>SGLT2 inhibitors<\/strong> (empagliflozin, dapagliflozin, canagliflozin) \u2014 now standard for diabetic CKD with eGFR \u226520 in many guidelines.<\/li>\n<li><strong>Finerenone<\/strong> \u2014 non-steroidal mineralocorticoid receptor antagonist for type 2 diabetes with CKD.<\/li>\n<li><strong>GLP-1 receptor agonists<\/strong> \u2014 show kidney benefit in cardiovascular outcome trials.<\/li>\n<li><strong>Tight glycaemic control<\/strong> \u2014 particularly important early.<\/li>\n<li><strong>Avoid NSAIDs<\/strong> for chronic pain in CKD where possible.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">FAQ<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Why doesn&#8217;t this calculator ask about race?<\/h3>\n\n\n\n<p>The 2021 CKD-EPI equation removed race as a variable. The previous equation used a Black-race coefficient that the National Kidney Foundation and American Society of Nephrology Task Force concluded was inappropriate. The race-free equation is now used by the NHS, NICE, KDIGO, and most US labs.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">What&#8217;s a normal eGFR?<\/h3>\n\n\n\n<p>Above 90 ml\/min\/1.73m\u00b2 is &#8220;normal.&#8221; eGFR also drops naturally with age \u2014 losing about 1 ml\/min\/1.73m\u00b2 per year after age 30. An eGFR of 75 in a 70-year-old is not the same clinical concern as 75 in a 35-year-old.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Can eGFR improve?<\/h3>\n\n\n\n<p>Yes \u2014 particularly when caught early. SGLT2 inhibitors initially cause a small drop in eGFR (3\u20135 ml\/min) within weeks, then stabilise the long-term decline. Other reversible factors include dehydration, untreated high blood pressure, NSAIDs, and decompensated diabetes.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Related<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/livingdiabetes.com\/ur\/diabetes-complications\/\">Diabetes Complications: kidney, heart, eye, foot<\/a><\/li>\n<li><a href=\"https:\/\/livingdiabetes.com\/ur\/the-uacr-test-your-best-defence-against-kidney-disease\/\">The UACR Test: your best defence against kidney disease<\/a><\/li>\n<li><a href=\"https:\/\/livingdiabetes.com\/ur\/sglt2-inhibitors-for-kidney-protection-a-powerful-tool\/\">SGLT2 Inhibitors for Kidney Protection<\/a><\/li>\n<li><a href=\"https:\/\/livingdiabetes.com\/ur\/calculators\/\">All diabetes calculators<\/a><\/li>\n<\/ul>\n\n\n\n<p><em>References: Inker LA, Eneanya ND, Coresh J, et al. New creatinine- and cystatin C\u2013based equations to estimate GFR without race. NEJM 2021;385:1737-1749. NICE NG203 (CKD). NICE NG28. KDIGO 2024 CKD guideline. Reviewed: May 2026.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Estimate kidney filtration rate from creatinine using the 2021 CKD-EPI race-free equation recommended by NICE and the NHS. With CKD staging and what each result means.<\/p>","protected":false},"author":4,"featured_media":3508,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-3490","page","type-page","status-publish","has-post-thumbnail","hentry"],"rttpg_featured_image_url":{"full":["https:\/\/livingdiabetes.com\/wp-content\/uploads\/2026\/05\/og_egfr-calculator.png",1200,630,false],"landscape":["https:\/\/livingdiabetes.com\/wp-content\/uploads\/2026\/05\/og_egfr-calculator.png",1200,630,false],"portraits":["https:\/\/livingdiabetes.com\/wp-content\/uploads\/2026\/05\/og_egfr-calculator.png",1200,630,false],"thumbnail":["https:\/\/livingdiabetes.com\/wp-content\/uploads\/2026\/05\/og_egfr-calculator-150x150.png",150,150,true],"medium":["https:\/\/livingdiabetes.com\/wp-content\/uploads\/2026\/05\/og_egfr-calculator-300x158.png",300,158,true],"large":["https:\/\/livingdiabetes.com\/wp-content\/uploads\/2026\/05\/og_egfr-calculator-1024x538.png",640,336,true],"1536x1536":["https:\/\/livingdiabetes.com\/wp-content\/uploads\/2026\/05\/og_egfr-calculator.png",1200,630,false],"2048x2048":["https:\/\/livingdiabetes.com\/wp-content\/uploads\/2026\/05\/og_egfr-calculator.png",1200,630,false],"trp-custom-language-flag":["https:\/\/livingdiabetes.com\/wp-content\/uploads\/2026\/05\/og_egfr-calculator-18x9.png",18,9,true],"post-thumbnail":["https:\/\/livingdiabetes.com\/wp-content\/uploads\/2026\/05\/og_egfr-calculator-300x158.png",300,158,true],"minimalistblogger-grid":["https:\/\/livingdiabetes.com\/wp-content\/uploads\/2026\/05\/og_egfr-calculator-350x230.png",350,230,true],"minimalistblogger-slider":["https:\/\/livingdiabetes.com\/wp-content\/uploads\/2026\/05\/og_egfr-calculator-850x446.png",850,446,true],"minimalistblogger-small":["https:\/\/livingdiabetes.com\/wp-content\/uploads\/2026\/05\/og_egfr-calculator-300x180.png",300,180,true]},"rttpg_author":{"display_name":"Claude SEO","author_link":"https:\/\/livingdiabetes.com\/ur\/author\/claude-seo\/"},"rttpg_comment":0,"rttpg_category":null,"rttpg_excerpt":"Estimate kidney filtration rate from creatinine using the 2021 CKD-EPI race-free equation recommended by NICE and the NHS. With CKD staging and what each result means.","_links":{"self":[{"href":"https:\/\/livingdiabetes.com\/ur\/wp-json\/wp\/v2\/pages\/3490","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/livingdiabetes.com\/ur\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/livingdiabetes.com\/ur\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/livingdiabetes.com\/ur\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/livingdiabetes.com\/ur\/wp-json\/wp\/v2\/comments?post=3490"}],"version-history":[{"count":1,"href":"https:\/\/livingdiabetes.com\/ur\/wp-json\/wp\/v2\/pages\/3490\/revisions"}],"predecessor-version":[{"id":3509,"href":"https:\/\/livingdiabetes.com\/ur\/wp-json\/wp\/v2\/pages\/3490\/revisions\/3509"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/livingdiabetes.com\/ur\/wp-json\/wp\/v2\/media\/3508"}],"wp:attachment":[{"href":"https:\/\/livingdiabetes.com\/ur\/wp-json\/wp\/v2\/media?parent=3490"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}