Overview
Fibromyalgia is a chronic condition characterised by widespread musculoskeletal pain, fatigue, sleep disturbance, and cognitive difficulties. It is thought to involve abnormal processing of pain signals in the brain, making the nervous system amplify normal sensations into significant pain.
How common is it?
Fibromyalgia appears to be relatively common, but its exact frequency is uncertain because diagnosis can be difficult. It is more common in women and often begins between ages 25 and 55, although it can occur at any age.
Causes and risk factors
The exact cause is unknown, but fibromyalgia involves central sensitisation, where the nervous system becomes hypersensitive to pain signals. Stressful physical or emotional events often precede onset.
Common risk factors
- Viral infection as a trigger in some people
- Physical or emotional trauma
- Female sex
- Family history of fibromyalgia
- Anxiety, depression, or post-traumatic stress
- Other rheumatic conditions (rheumatoid arthritis, lupus)
- Sleep disorders
Symptoms
- Widespread musculoskeletal pain in multiple body areas
- Fatigue despite sleeping, unrefreshing sleep
- Cognitive difficulties ('fibro fog'): poor memory, difficulty concentrating
- Headaches
- Irritable bowel symptoms
- Sensitivity to heat, cold, light, and noise
- Anxiety and depression
When to see a doctor
See a GP for persistent widespread pain, fatigue or sleep problems. Do not wait 3 months before seeking help. The clinician will assess other treatable causes and whether fibromyalgia is likely.
Diagnosis
Diagnosis is based on persistent widespread pain and associated symptoms. There is no single diagnostic test. A clinician may use blood tests to look for other causes, such as thyroid disease or inflammatory illness; fibromyalgia can coexist with other conditions.
Treatments
Aerobic exercise
The most evidence-based treatment for fibromyalgia. Gradual, paced increase in aerobic exercise (swimming, walking, cycling) reduces pain and fatigue over time. Start gently and build very slowly.
Medications
Amitriptyline or duloxetine may be considered for pain and sleep after discussing benefits and harms. UK NICE guidance advises against starting gabapentinoids such as pregabalin, NSAIDs, paracetamol or opioids for chronic primary pain, including fibromyalgia. If already taking them, arrange a medication review; do not stop abruptly.
Cognitive behavioural therapy
Helps people manage the impact of chronic pain on daily functioning, improve coping strategies, and address accompanying depression or anxiety.
Self-care and lifestyle
- Prioritise sleep hygiene: regular bed times, cool dark quiet room, avoid screens
- Use pacing strategies to avoid boom-bust cycles of overactivity followed by flare
- Warm baths or hydrotherapy can reduce pain temporarily
- Build a support network and connect with fibromyalgia peer support groups
Prevention
There is no established way to prevent fibromyalgia. Sleep support, paced activity and stress management may help people manage symptoms, but are not proven to prevent the condition.
Sources for targeted updates
Updated: 24 October 2026. Targeted corrections to treatment, diagnosis, urgent-care guidance, prevention, frequency. This update covers the named sections; a full review of the remaining guide is pending.